Medical Chinese(I) Cancer Treatment





Today, JYang wish to talk with you about medical problems, especially the treatment of cancer. This is the first time for us to touch Medicin Chinese.

我们先学习几个重点词语 First let's learn some key words:


1. 治zhì疗liáo treatment

2. 治zhì愈yù cure

3. 化huà疗liáo chemotherapy

4. 手shǒu术shù surgery operation

5. 放fànɡ疗liáo radiotherapy

6. 免miǎn疫yì系xì统tǒnɡ immune system

7. 基jī因yīn检jiǎn测cè DNA testing

8. 靶bǎ向xiànɡ治zhì疗liáo targeted therapy

9. 高ɡāo血xuè压yā hypertension

10. 糖tánɡ尿niào病bìnɡ diabetes

11. 白bái血xuè病bìnɡ leukemia

12. 淋lín巴bā瘤liú lymphoma

13. 肺fèi癌ái lung cancer

14. 胃wèi癌ái gastric cancer

15. 基jī因yīn突tū变biàn gene mutation

16. 精jīnɡ准zhǔn诊zhěn疗liáo precise diagnosis and treatment

17. 细xì胞bāo免miǎn疫yì疗liáo法fǎ cellular immunotheratpy

18. 疫yì苗miáo vaccine



As is known to all, the importance of information in modern society is self-evident. In a certain sense, information can determine our success or failure.



Terrible cancer is a major killer of human beings and so is called incurable disease. With the development of science and technology, cancer can now be controlled and alleviated, and even there are many cases of complete cure, thus patients gain hopes for life. However, JYang maintains ideas from the past experience that the key to cancer patients' hopes for life lies in mastering the information. Now let's learn the latest information on cancer treatment.



The three ways, like three swordsmen, of traditional cancer treatment include chemotherapy, surgery operation and radiotherapy. Although there are now powerful drugs such as paclitaxel, carboplatin and cisplatin, which can quickly control certain cancers, after all, chemotherapy is a way of “killing one thousand and losing eight hundred”, also very harmful to the patient himself. In particular, it reduces the function of the immune system to fight cancer. According to statistics, even the medicine has effect after chemotherapy, 80% of patients will still develop drug resistance or relapse. Traditional surgery and radiotherapy can't cure cancer thoroughly. Like chemotherapy, patients suffer a lot from them.


In recent years, the study and development of a new generation of anti-tumor drugs has led to the entry of cancer drug therapy into a new era of precise targeted therapy based on genome sequencing test (ie, genetic testing). A large number of clinical cases have proven that molecular targeted therapy not only accurately "kills" cancer cells, but also effectively prevents the development of tumors, so as to achieve the so-called "survival with tumor", making cancer a "chronic disease" similar to hypertension and diabetes.



Some cancers can be directly targeted to treatments, such as leukemia, because most of such patients have mutations in the BCR-ABL gene, and the famous "medicine" Gleevec can directly save their lives.




However, more cancers treatment need badly genetical test because different targeted drugs target different target points, so genetic test aiming at determining if a suitable target point exists. In order to promote the effect or prevent drug resistance, it is also possible to use a combination of targeted drugs, use targeted drugs with chemotherapy drugs.



At present, targeted drugs approved by the US Food and Drug Administration (FDA) are mainly used for: gastric cancer, bladder cancer, brain cancer, breast cancer, cervical cancer, colorectal cancer, cutaneous sarcoma, head and neck cancer, neuroendocrine tumor, gastrointestinal stromal tumor, giant cell tumor of bone, kidney cancer, leukemia, liver cancer, lung cancer, lymphoma, multiple myeloma, neuroblastoma, epithelial ovarian cancer, primary peritoneal cancer, pancreatic cancer, prostate cancer , soft tissue sarcoma, thyroid cancer, and solid tumors with NTRK or microsatellite defects.



In addition, about 14 targeted drugs of small molecules do not require genetic testing, such as bevacizumab, everolimus, levabinib, pazopanib, and so on.



By the way, genetic testing. Cancer is basically a genetic disease, so genetic testing has become the standard procedure for cancer diagnosis and treatment in the last two years. In research hospitals, each patient has his own pathological and genetic test reports to achieve individualized precise diagnosis and treatment plan for each patient. Genetic testing is to discove genes that are mutated, some missing, some repetitive, and some skewed, and so on. This is just the difference between cancer cells and normal cells.



Next let's continue our talk about cellular immunotherapy that is considered to be able to overcome cancer completely. Not long ago, the United States and Japan officially approved two CAR-T therapies, which have brought leukemia and lymphoma treatment into a new era. Immunotherapy has gradually attracted the biggest attention of medical research institutions and research hospitals. Recently all the countries have intensive research on intensifying immunotherapy techniques, including DC cells (dendritic cells, represented by Germany and Japan. The 2011 Nobel Prize in Medicine was specially awarded to three scientists who made outstanding contributions to the breakthrough research of DC cells on cancer therapy) , NK cells, TIL cells, etc., and the progress is huge and optimistic.



The underlying cause of cancer is that the patient's own immune system is unable to control the development and progression of cancer cells, or is owing to reduced immunity or the inability to recognize cancer cells. Therefore, immunotherapy has become the key to completely cure cancer.



Depending on the cancer situation, the following immunotherapies can be chosen: cellular immunotherapy (cultivating immune cells in vivo and then removing cancer cells by blood transfusion), dendritic cell vaccine, CAR-T therapy, and other T cell therapies.



By the way, the therapeutic cancer vaccine. The first anti-cancer vaccine successfully developed in the world is Cuba's successful CIMAvax lung cancer vaccine after 25 years of research. Vaccine therapy can be said to be a breakthrough in cancer treatment. Vaccine treatment is very simple, just a shot on the arm, but vaccine therapy functions by activating human immune cells, especially T cells (including regulatory T cells and killer T cells) and NK cells, which then kill cancer cells. At present, Cuba, the United States, China, Germany, Japan have successful developed their respective vaccines for early and advanced non-small cell lung cancer, colorectal cancer, prostate cancer, head and neck cancer, pancreatic cancer, esophageal cancer, gastric cancer and metastatic cancers, etc.




Additionally, in recent years, there have been many black technologies for cancer treatment, such EDGE, proton or heavy ion therapy, electric field therapy, and hot irrigation therapy, viral therapy, which have brought many cancer patients hopes for cure.




Ok, so much for today’s talk. If you like it, in the future we will conduct more in-depth studies on cancer treatment, share the experience of learning, and learn more medical knowledge and medical Chinese.


未完待续 To be continued



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